The Neuroscience of Deep Brain Stimulation: Research and Clinical Applications

Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, including developmental experimental models for movement and psychiatric disorders. The second section reviews various clinical applications, including numerous and in-depth case studies. The final section identifies the mechanisms of action behind DBS, including cellular, metabolic, and neurochemical mechanisms. Internationally contributed, this book is an essential guide for anyone in the field of DBS.

Περιεχόμενα:

Part 1: Bench
1. The quest for a target and the beginning of the DBS-story
2. Early clinical application
3. Development of experimental models for movements disorders
4. Development of experimental models for psychiatric disorders

Part 2: Science behind the clinical application
5. Parkinson’s disease
6. Dystonia
7. Essential tremor
8. Epilepsy
9. OCD
10. Tourette Syndrome
11. Depression
12. Alzheimer’s disease
13. Other indications

Part 3: Mechanisms of action
14. Neurophysiological mechanisms
15. Cellular mechanisms
16. Metabolic mechanisms
17. Neurochemical mechanisms
18. Mechanisms investigated by imaging

Part 4. Future/perspectives