Metabolites as Signals in Immunity and Inflammation

Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinking about the whole field of immunology. These changes occur thanks to breakthrough experiments in basic research, and with the help of new technologies that allow for the testing of immunology hypotheses. In recent years, a substantial number of findings have been made around immunometabolism. What is emerging is a complex interplay between metabolic reprogramming and immunity, which is providing an extra dimension to our understanding of the immune system in health and disease.

Χαρακτηριστικά:

• Provides insights into novel immunotherapeutic targets.
• Brings together personalized medicine, physiology, and immunobiology.
• Describes the changes that occur in intracellular metabolic pathways in immune cells during activation.
• Highlights changes in thinking about the field of immunology.

Περιεχόμενα:

1. Intro chapter: broad intro
2. Host-microbe interactions and the role of immunometabolism
3. Immunometabolism and human diseases
4. Cell Death and Metabolism
5. Oncology and Metabolism
6. Cardiovascular System and Metabolism
7. Innate Immunity and Metabolism
8. Adaptive Immunity and Metabolism
9. Autoimmunity and Metabolism
10. Epigenetics and Innate Memory Metabolism
11. Diabetes, Obesity, and Metabolism
12. Metabolism as a Portal to New Therapeutics