Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-Infective and Anti-Cancer Drugs

Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure–activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any.

This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents.

Περιεχόμενα:

1. Introduction to Chemotherapy: General and Clinical Considerations

Section A. ANTIMICROBIAL AGENTS
Unit I Antibacterial Agents
2. Sulfonamides, Quinolones, Antiseptics and Disinfectants
Unit II Antibacterial Antibiotics
3. Beta-Lactam Antibiotics: Penicillins, Cephalosporins, Monobactams, Carbapenems and Beta-lactamase Inhibitors
4. Tetracyclines and Chloramphenicol
5. Aminoglycoside Antibiotics
6. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics
Unit III Antimycobacterial Agents
7. Antitubercular Drugs
8. Antileprotic Drugs
Unit IV Antifungal Agents
9. Topical and Systemic Antifungal Drugs
Unit V Antiviral Agents
10. Antiviral Drugs and Vaccines
Unit VI Antiprotozoal Agents
11. Antimalarial Drugs
12. Antiamoebic Drugs
13. Drugs for Giardiasis, Trichomoniasis and Leishmaniasis
UNIT VII Anthelmintics
14. Vermifuge and Vermicide Drugs

Section B ANTINEOPLASTIC AGENTS
15. Synthetic Cytotoxic Drugs as Cancer Chemotherapeutic Agents
16. Naturally Occurring Anticancer Cytotoxic Drugs
17. Hormones and Antihormones in Cancer Chemotherapy
18. Biologicals and Small Molecules as Target Specific Cancer Chemotherapeutic Agents